System description & applications
This system is used to perform continuous motion imaging of large samples on multi-well plate supports at a very high frame rate.
INSCOPER has replaced some of the existing system’s devices and integrating a dedicated sub-system (or module) for continuous motion imaging. Our engineers have also updated and automated the Zeiss Axio Observer Z1 microscope system to perform the continuous motion imaging workflow.
The system is installed at the National Institute of Standards and Technology (NIST; Gaithersburg, Maryland, USA).
The Inscoper technology has become an essential part of our image collection workflow. The Inscoper controlled automated microscope operates more than 5x faster. This allows us to generate training data for deep learning-based analysis much more efficiently and allows us to perform dynamic single cell measurements with much deeper sampling than otherwise possible.
Michael Halter
National Institute for Standards and Technology (NIST),
Cell Systems Science Group, Gaithersburg, Maryland, USA
microscope device list
- Microscope: Zeiss Axio Observer Z1
- LED source for short illumination bursts:
- Märzhäuser LED 100
- Märzhäuser DSU-1 controller unit for LED 100
- Cameras:
- 2x Hamamatsu Fusion BT
- LED source for fluorescence excitation
- Fluorescence Illumination System CoolLed pE-4000
- x-y scanning stage and piezo stage:
- Märzhäuser SCANplus IM 130 × 100
- Controller Tango 2