Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2

Aug 18, 2020 | Publications

Giulia Bertolin, Marie-Clotilde Alves-Guerra, Agnès Burel, Claude Prigent, Roland Le Borgne and Marc Tramier

BioRxive Preprint Server for Biology (10.1101/2020.04.06.027896v1)

FRET by FLIM analyses detect the interaction between the multifunctional Ser/Thr kinase AURKA-GFP and the autophagy marker mCherry-MAP1LC3 at sites of autophagosome formation (dashed area). The interaction is abolished with the autophagy-impairing drug Xanthohumol.


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